Cytomark are pleased to announce the launch of their TransFix/EDTA CSF Sample Storage Tubes as CE marked in vitro diagnostic devices. Below we present finding on the effect of TransFix on cerebrospinal fluid samples, when compared to untreated samples, and …
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Preservation of CD34+ Stem Cells and Precursors with TransFix
CD34+ population enumeration has multiple applications, for example to indicate whether a hematopoietic stem-cell harvest is ready to be performed for transplant, or to characterise progenitor/precursor populations such as B-cell precursors in Acute lymphoblastic leukaemia (ALL) samples. However, rare CD34+ …
Read MorePreservation of mRNA from Isolated Circulating Tumour Cells
It is well documented that TransFix treated blood is compatible with isolation of circulating tumour cells, but new work published by Baird et al. describes a novel method of isolating CTCs, and the first published method of extracting mRNA from …
Read MoreStromal Vascular Fraction (SVF) Stabilisation
Applications of TransFix: Stabilisation of Adipose-derived Stromal Vascular Fraction (SVF) Independent research involving the use of TransFix to stabilise Adipose derived Stromal Vascular Fraction (SVF) for flow cytometry has been published. Stromal vascular fraction (SVF) from adipose tissue contains a …
Read MoreBronchoalveolar lavage fluid (BALF) Stabilisation
Applications of TransFix: Stabilisation of Bronchoalveolar lavage fluid (BALF) Independent research involving the use of TransFix to stabilise BALF samples has been published, including the use of TransFix for the enumeration of rat leucocytes present in BALF (case study 1). …
Read MoreTransFix Compatible Antibodies
TransFix is designed to stabilise TBNK surface markers for up to 14 days for flow cytometry analysis. Researchers around the world use TransFix to stabilise over 100 different cellular markers. Cytomark have compiled a list of cellular markers and their …
Read MoreAnimal Blood Stabilisation
TransFix® Has Been Used to Prevent Cellular Degradation in Animal Blood for Analytical Testing Purposes Like with human whole blood specimens, animal whole blood degrades over time rendering it unsuitable for examination. Researchers have found that the addition of TransFix …
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TransFix Stabilisation of Malignant Haematological Cells in Cerebrospinal Fluid
Flow Cytometric Analysis of Cerebrospinal Fluid (CSF) Invasion of leucocytes into cerebrospinal fluid has grave prognostic significance and requires important therapeutic decisions including the administration of intrathecal chemotherapy. Leptomeningeal localisation is conventionally diagnosed by cytomorphological analysis through identification of malignant …
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Bone Marrow Stabilisation
Applications of TransFix: Stabilisation of Bone Marrow for Flow Cytometry Bone marrow (BM) examination is an essential procedure for the evaluation of a variety of clinical haematologic disorders and for preclinical toxicity studies of anti-cancer compounds and immunosuppressive agents. This …
Read MoreBlood Stabilisation: The Importance in a Clinical Setting
Without stabilisation, flow cytometric analysis of blood samples must be performed within 48 hours of venepuncture, as apoptosis and proteolytic degradation of cellular markers will detrimentally affect the immunophenotypic profile. Blood samples older than 48 hours are often no longer …
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