CD34+ population enumeration has multiple applications, for example to indicate whether a hematopoietic stem-cell harvest is ready to be performed for transplant, or to characterise progenitor/precursor populations such as B-cell precursors in Acute lymphoblastic leukaemia (ALL) samples. However, rare CD34+ …
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Stabilisation of Circulating Endothelial Progenitor Cells
TransFix stabilises lymphocytes for up to 14 days, but other cell populations have also been shown to be stable with TransFix. One example is Circulating Endothelial and Endothelial Progenitor Cells which have been referenced by multiple papers: TransFix for Delayed …
Read MoreInnovative Applications of TransFix – March 2020
TransFix is designed for stabilisation of peripheral blood and cerebrospinal fluid to enumerate lymphocyte subpopulations by flow cytometry. However, researchers have developed many new and innovative uses of TransFix. We have highlighted publications showing the versatility of TransFix. Read on …
Read MoreStromal Vascular Fraction (SVF) Stabilisation
Applications of TransFix: Stabilisation of Adipose-derived Stromal Vascular Fraction (SVF) Independent research involving the use of TransFix to stabilise Adipose derived Stromal Vascular Fraction (SVF) for flow cytometry has been published. Stromal vascular fraction (SVF) from adipose tissue contains a …
Read MoreBronchoalveolar lavage fluid (BALF) Stabilisation
Applications of TransFix: Stabilisation of Bronchoalveolar lavage fluid (BALF) Independent research involving the use of TransFix to stabilise BALF samples has been published, including the use of TransFix for the enumeration of rat leucocytes present in BALF (case study 1). …
Read MoreTransFix Compatible Antibodies
TransFix is designed to stabilise TBNK surface markers for up to 14 days for flow cytometry analysis. Researchers around the world use TransFix to stabilise over 100 different cellular markers. Cytomark have compiled a list of cellular markers and their …
Read MoreLymph Node Stabilisation
Applications of TransFix: TransFix® Can Be Used to Stabilise Lymph Node Biopsies/Fine Needle Aspirate Specimens for Flow Cytometry Time is critical for the enumeration of cells from lymph node biopsies and other solid tissue via flow cytometry, because cells and …
Read MoreExtracellular Vesicle Isolation from TransFix Stabilised Blood: Preservation of exosome profiles
There has been increasing interest in extracellular vesicles (the “Exosome”) as possible biomarkers for disease and as novel cell-cell communicators. Extracellular vesicles (EVs) carry a variety of cargo such as mRNA, non-coding RNA, proteins and lipids and are thought to …
Read MoreAnimal Blood Stabilisation
TransFix® Has Been Used to Prevent Cellular Degradation in Animal Blood for Analytical Testing Purposes Like with human whole blood specimens, animal whole blood degrades over time rendering it unsuitable for examination. Researchers have found that the addition of TransFix …
Read MoreBone Marrow Stabilisation
Applications of TransFix: Stabilisation of Bone Marrow for Flow Cytometry Bone marrow (BM) examination is an essential procedure for the evaluation of a variety of clinical haematologic disorders and for preclinical toxicity studies of anti-cancer compounds and immunosuppressive agents. This …
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