CD34+ population enumeration has multiple applications, for example to indicate whether a hematopoietic stem-cell harvest is ready to be performed for transplant, or to characterise progenitor/precursor populations such as B-cell precursors in Acute lymphoblastic leukaemia (ALL) samples. However, rare CD34+ …
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Stabilisation of T-Cell Activation Markers
Measurement of T-cell activation can be important when assessing immune responses, however cells can become artificially activated over time once removed from the body. TransFix has been used to stabilise activated T-cell populations. We’ve presented a selection of publications to …
Read MoreTransFix Stabilisation of Blood Collected on Heparin Anticoagulants
Cytomark have validated TransFix for use with EDTA anticoagulant for lymphocyte phenotyping, however there are publications documenting the successful use of other anticoagulants such as heparin. Below are 2 examples of clinical trials where TransFix has been added to blood …
Read MoreTransFix Compatible Antibodies
TransFix is designed to stabilise TBNK surface markers for up to 14 days for flow cytometry analysis. Researchers around the world use TransFix to stabilise over 100 different cellular markers. Cytomark have compiled a list of cellular markers and their …
Read MoreBlood Stabilisation: The Importance in a Clinical Setting
Without stabilisation, flow cytometric analysis of blood samples must be performed within 48 hours of venepuncture, as apoptosis and proteolytic degradation of cellular markers will detrimentally affect the immunophenotypic profile. Blood samples older than 48 hours are often no longer …
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